Viral determinants of influenza A virus host range
نویسندگان
چکیده
منابع مشابه
Influence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase
Avian influenza A viruses often do not propagate efficiently in mammalian cells. The viral polymerase protein PB2 is important for this host restriction, with amino-acid polymorphisms at residue 627 and other positions acting as 'signatures' of avian- or human-adapted viruses. Restriction is hypothesized to result from differential interactions (either positive or inhibitory) with unidentified ...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2014
ISSN: 0022-1317,1465-2099
DOI: 10.1099/vir.0.062836-0